A short interview with science writer James Gleick on his new book 'Information' that I think has some interesting parallels with My Big Toe -
Kelly: The extreme view would be that all these bits that make up atoms are running on a very big computer called the universe, an idea first espoused by Babbage.
Gleick: That makes sense as long as this metaphor does not diminish our sense of what the universe is but expands our sense of what a computer is.
Kelly: But as you note, some scientists say that this is not a metaphor: The universe we know is only information.
Here is the link to the interview at Wired - http://www.wired.com/magazine/2011/02/mf_gleick_qa/