For instance any "anger management" issue that we may have, in my opinion, is likely to come from the wiring of our brain and /or whether or not the adults who cared for us when we were very young responded appropriately to our needs (ie Attachment Theory).
Yes this has also been an area of concern. Not only is a large part of our personality based on genetics but I feel that a lot of psychological problems are rooted in childhood experiences and adolescent experiences (psychologists would probably agree). Those experiences seem rather random. For example a person born in a household where there was abuse would likely develop a lot of personality issues later on in life (addiction, depression, etc) that they would have to deal with. How does this relate back to NPMR/IUOC?
Also, it seems that most of the learning in our modern world doesn't translate very much outside of the virtual reality. A person can spend a lot of time in school/work learning something, but all that knowledge is for a specific skill that only applies in PMR. It looks to me like it's mostly a waste of time.